For the treatment of cattle and other productive animals, it is preferable to use universal complex preparations. They are able to cope with various infections, have an extended spectrum of action and have a minimum of contraindications. The category of such effective drugs includes "Nitox" - a solution of antibiotics, which is administered intramuscularly.
Description and composition
Nitox 200 is a tetracycline antibiotic in the form of a liquid. The product is produced by the domestic pharmaceutical company Nita-Pharm. The drug is packaged in dark glass bottles, closed with rubber stoppers and rolled in aluminum foil. The contents of the vial are sterile, the vial has a corresponding mark. Use with damaged packaging is excluded.
The drug is a dark brown viscous liquid with a characteristic odor. A slight sediment is allowed. The most popular packing is 20, 50, 100 ml. Vials are packed in cardboard boxes and supplied with instructions. Part of the information about the drug is indicated on the label. The date of issue, batch number, information about the manufacturer are also indicated. After the expiration date, it is prohibited to use the medicine.
The main active ingredient of the drug is oxytetracycline (200 mg per 50 ml of the finished solution). There are also excipients:
- magnesium oxide;
- dimethylacetamide;
- rongalid;
- monoethanolamine;
- purified water for injection.
"Nitox 200" can be used within 18 months from the date of manufacture (provided that the bottle is kept sterile). The drug should be stored away from food and medicine, out of the reach of young children and animals. Do not place bottles next to heating devices, freezing is also undesirable. The best storage option: a cool, dark place with a temperature of 0 to 10 degrees.
The drug is sold in all veterinary pharmacies at a price of 40-50 rubles for a 20 ml bottle. It is recommended to consult a veterinarian before use.
Indications and contraindications
The drug is intended for the treatment and prevention of cattle, pigs, sheep and goats. It is forbidden to use the product for horses, dogs, cats and other unproductive pets.
"Nitox" is effective for the treatment of infectious and fungal diseases that are sensitive to tetracycline drugs. Nitox injections are prescribed for:
- pneumonia;
- mastitis;
- diphtheria;
- anaplasmosis;
- pneumonia;
- sepsis;
- pleurisy;
- conjunctivitis;
- rhinitis;
- purulent arthritis;
- erysipelas;
- wound infections and abscesses;
- hoof rot;
- peritonitis;
- avitaminosis;
- enzootic abortion;
- postpartum infections.
The drug is also suitable for prophylaxis, as well as for the suppression of secondary infections and fungal infections that occur against the background of more serious diseases. When treating, it is advisable to consult a veterinarian. An examination is also needed after completing the course: it will confirm that the therapy was carried out successfully. According to the doctor's indications, the course can be repeated or lengthened.
There are few contraindications for Nitox 200. The main thing is an individual allergic reaction to the main and accompanying components. The medicine is not suitable for the treatment of animals with renal failure. It is not recommended to use the drug simultaneously with corticosteroids and estrogens. If the animal is undergoing complex antibiotic treatment, it is important to ensure that Nitox is not used simultaneously with penicillin and cephalosporin drugs. They significantly reduce the effectiveness of tetracycline and its derivatives.
There are restrictions related to productive livestock. During treatment, milk from cows, sheep and goats should not be eaten. It is siphoned off and poured out. You can use milk for fattening calves, but only after heat treatment.
Slaughter of animals for meat can be carried out no earlier than 20 days after injection. Otherwise, the meat becomes unsuitable for eating, it is processed into meat and bone meal or fed to animals.
Small side effects are possible during the treatment with Nitoks. After injections, some animals develop swelling at the puncture site, skin redness, itching. Usually, these manifestations go away on their own, without additional treatment. But if the animal is worried, you can relieve negative symptoms with calcium supplements that are administered intravenously.
Operating principle
When injected intramuscularly, the active substance quickly enters the blood and tissues. Oxytetracycline inhibits the activity of gram-negative and gram-positive bacteria. Effective against staphylococci and streptococci, salmonella, actinobacteria, spirochetes, salmonella, pasteurella, fusobacteria. The fast action is due to the combination of oxytetracycline and magnesium oxide, which increases the rate of penetration of the antibiotic into tissues. The maximum concentration of active components in the blood is observed 30-60 minutes after injection.
The drug has a cumulative effect, after administration it remains in the muscles and organs, preventing secondary infection. The therapeutic effect lasts up to 3 days. The remains of the drug are excreted along with urine and bile. In animals that have recently given birth, active and accompanying substances pass into milk.
According to the GOST classification, "Thread 200" belongs to the 3rd hazard class (moderate). During work, it is necessary to strictly observe hygiene measures, the remnants of the drug are disposed of, the packaging from the medicine must not be reused.
Method of administration and dosage
The drug is injected deep into the muscle. The advantage of Nitoks is the limited number of injections. Usually, 1 injection is enough to eliminate bacterial and fungal infections; in difficult cases, the procedure is repeated after 3 days.
Before the procedure, you need to take personal safety measures by wearing rubber gloves. In case of accidental contact with the skin, the drug is washed with a damp cloth; in case of contact with mucous membranes, it is necessary to rinse them with plenty of running water. It is forbidden to eat, drink or smoke while injecting.
The dose is calculated individually and depends on the weight of the animal. For 10 kg of live weight, you will need 1 ml of the drug. At the same time, the instruction specifies that a limited amount of the drug can be injected at one point: up to 20 mg for cattle, up to 8-10 for pigs and up to 5 for goats, sheep and other small animals. If necessary, the dose is divided into 2 parts and injected into different places, and this should be done with a minimum time interval.
You need to inject the drug deep into the muscle. Most animals tolerate injections calmly, for better distribution, you can gently massage the injection site.
Benefits of the drug
Veterinarians and farmers rate Nitox 200 quite highly. The reviews indicate the main advantages of the drug:
- Multifunctionality. The product is suitable for eliminating bacterial and fungal infections of productive pets, including secondary ones. Has a cumulative effect.
- Efficiency. Active substances enter the bloodstream within a few minutes after administration and persist up to 3 days.
- Availability. The product is inexpensive and sold in all veterinary pharmacies. For a complete cure of the animal, 1-2 injections are enough.
- High quality. The patented technology and the company's reputation guarantee the authenticity and effectiveness of the drug.
"Nitox" is a multifunctional drug that helps against many diseases of cattle and other domestic animals. The tool has almost no contraindications, with the correct dosage and choice of a course, it does not affect the quality of meat and milk.